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Selinexor (Xpovio) — 2026 Medicare Part D coverage

Contract year 2026 · CMS monthly formulary file · drug names from RxNorm · data updated October 01, 2026

selinexor — sold as Xpovio: 8 forms appear in Medicare Part D formularies for 2026. This page reports what plans filed with CMS; it does not recommend a plan.

100%of 328 formularies list the most-covered form
Tier 5most common tier
99%report prior authorization (max across forms)
79%report a quantity limit

Which plans in your county cover selinexor?

Pick a county to see every Medicare Advantage plan filed there and every stand-alone Part D plan in its region, with this drug's tier, restrictions and tier cost sharing.

Forms and strengths in 2026 formularies

FormFormularies listing itMost common tierPASTQL
XPOVIO 100 MG Weekly Dose (50 MG Tablet) Carton Pack
brand · RxCUI 2548742
328 (100%)53260255
XPOVIO 40 MG Twice Weekly Dose (40 MG Tablets) Carton Pack
brand · RxCUI 2548767
328 (100%)53260258
XPOVIO 40 MG Weekly Dose (10 MG Tablet) Carton Pack
brand · RxCUI 2708339
328 (100%)53240248
XPOVIO 60 MG Twice Weekly (120 MG total weekly) Dose Carton Pack
brand · RxCUI 2382990
328 (100%)53260255
XPOVIO 60 MG Weekly Dose (60 MG Tablet) Carton Pack
brand · RxCUI 2548736
328 (100%)53260255
XPOVIO 80 MG Twice Weekly (160 MG total weekly) Dose Carton Pack
brand · RxCUI 2178407
328 (100%)53260253
XPOVIO 80 MG Weekly Dose (40 MG Tablets) Carton Pack
brand · RxCUI 2548766
328 (100%)53260258
XPOVIO 80 MG Weekly Dose (80 MG Tablet) Carton Pack
brand · RxCUI 2730156
327 (100%)53260255

Counts are formularies (of 328) in the CMS file that list the form, and how many of those apply prior authorization (PA), step therapy (ST) or a quantity limit (QL). Many plans share one formulary, so plan counts in a county will differ.

How to read drug coverage

Tier is the cost-sharing tier the plan assigned the drug in its CMS formulary filing; lower tiers usually cost less. PA = prior authorization, ST = step therapy (try another drug first), QL = quantity limit. Not on formulary means the plan did not list this exact form; the plan may cover another strength or a formulary exception may be possible. Cost sharing is the plan's initial-coverage amount for the tier as filed with CMS; the deductible, the $2,100 annual out-of-pocket cap, the $35 insulin cap and negotiated prices for selected drugs can change what you actually pay. Formularies change during the year; the plan's formulary document and Medicare.gov govern.

What the star rating under each Medicare Advantage plan means

What the star rating means. CMS rates every Medicare Advantage contract (the "H" number in the plan ID — all plans under it share the rating) on a 1-to-5 scale each October, from about 40 measures of care quality, member experience, complaints and appeals, customer service and, for plans with drug coverage, drug safety and pricing. The 2026 rating is largely based on performance measured in 2024.

5 Excellent4 Above average3 Average2 Below average1 Poor

Not rated means CMS published no overall rating — usually a contract too new to be measured or with too few members ("not enough data"); it is not a low score. A 5-star contract can be joined outside the normal enrollment windows (the 5-star Special Enrollment Period, Dec 8 – Nov 30). Medicare.gov flags contracts rated below 3 stars for three years running as low-performing. Stars describe the contract's past performance as CMS measured it; they are not a recommendation, and they do not tell you whether a plan's network, drugs or costs fit you.